Why Am I Not Losing Weight on Ozempic or Mounjaro? (And What to Do About It)

Weight loss injections like Ozempic, Mounjaro, and other GLP-1 medications have transformed the weight loss journey for many. But what happens when the results stop? Or worse—never start at all?

If you’re wondering, “Why am I not losing weight on Ozempic?”, you’re not alone. This is one of the most Googled questions about weight loss injections. In this post, we’re breaking down the real reasons why it happens and what you can do next.

🔍 Is It Normal to Hit a Weight Loss Plateau on GLP-1?

Yes—plateaus are extremely common. Even if you’re taking your injection exactly as prescribed, there are several reasons why your weight loss may slow down or stall completely.

Common reasons for plateau or slow progress on Ozempic or Mounjaro:

• You’re undereating, which slows metabolism

• You’re not eating enough protein or missing nutrients

• You’re dehydrated, which affects appetite and fat loss

• You’re relying on the injection without adjusting your lifestyle

• Your dose may need adjusting—or you’ve increased too soon

🧬 Are You a Non-Responder?

Some people experience minimal or no weight loss with GLP-1s. This is called GLP-1 non-response, and it’s more common than most realise.

You may be a non-responder if:

• You’ve been on a full dose for 3+ months with less than 5% weight loss

• You feel no appetite suppression

• You have underlying conditions (e.g. hypothyroidism, insulin resistance)

• You rely on emotional eating, which the injection doesn’t fully address

But don’t give up. There are always next steps, and you don’t have to navigate them alone.

✅ What You Can Do to Restart Your Weight Loss

If your results have slowed or stopped completely, try this before changing your dose:

1. Track your protein intake — aim for at least 60–90g per day, but your exact requirements could be higher

2. Stay hydrated — 2–3L daily makes a difference

3. Move your body — even light daily activity helps. If you are already exercising then change up the type of exercise you're doing. If you can, try to incorporate strength training.

4. Address stress and sleep — hormones matter too. Poor sleep and increased stress can prevent weight loss.

5. Seek expert support — guidance = faster, smarter progress. Speak to a dietitian or psychologist.

💡 You Don’t Have to Do This Alone

At HealthyMe Weight Loss, we help people just like you:

• Break through frustrating plateaus

• Understand their GLP-1 dose and nutrition needs

• Decide when (and if) weight loss surgery is the right next step

• Feel confident and in control again

Our Complete GLP-1 Weight Loss Guide is designed by a registered dietitian and packed with everything you need to get results—not just from the injection, but from the lifestyle changes that make them last.

👉 Learn more & download the guide here

Or if you’re wondering whether surgery is your next step, enquire now to speak with our team.